pfasUCMR5Unregulated by EPA

ADONA (4,8-dioxa-3H-perfluorononanoic acid)

Reviewed for accuracy against EPA data and peer-reviewed literature · Updated May 2026

ADONA is a short-chain ether PFAS used as a replacement for PFOA in the manufacture of fluoropolymers, particularly by 3M under the trade name "Dyneon." Like HFPO-DA (GenX), it contains ether linkages that distinguish it structurally from straight-chain PFAS. It has been detected in water near fluoropolymer manufacturing facilities in Europe and the US.

CAS 919005-14-4

EPA legal limit

No federal limit

Maximum Contaminant Level

EWG health guideline

No guideline

Science-based, stricter target

Health effects

Toxicological data on ADONA is limited. Animal studies show liver effects and peroxisome proliferation consistent with PFOA-type compounds. Its ether linkage was initially thought to reduce bioaccumulation potential, but it has been detected in human blood samples near contamination sources. It is not known to be metabolised to PFOA.

Where it comes from

Industrial use as a polymerisation aid in fluoropolymer manufacturing, developed as a PFOA replacement. Detected in water near manufacturing facilities. Included in UCMR5 due to concern about PFOA replacement chemicals entering drinking water supplies.

How it's regulated

No federal EPA MCL. Not individually regulated under the 2024 PFAS NPDWR. Monitored under UCMR5. No EWG health guideline established due to limited toxicological data.

How to filter adona

Not all filters address adona. Look for independently certified filters—NSF International certification means the removal claim has been independently verified.

Reverse osmosis (RO)NSF 58
NSF 58 certified RO system
Activated carbon block filterNSF 53

Frequently asked questions

What is adona?

ADONA is a short-chain ether PFAS used as a replacement for PFOA in the manufacture of fluoropolymers, particularly by 3M under the trade name "Dyneon." Like HFPO-DA (GenX), it contains ether linkages that distinguish it structurally from straight-chain PFAS. It has been detected in water near fluoropolymer manufacturing facilities in Europe and the US.

What are the health effects of adona?

Toxicological data on ADONA is limited. Animal studies show liver effects and peroxisome proliferation consistent with PFOA-type compounds. Its ether linkage was initially thought to reduce bioaccumulation potential, but it has been detected in human blood samples near contamination sources. It is not known to be metabolised to PFOA.

Is adona regulated in drinking water?

No federal EPA MCL. Not individually regulated under the 2024 PFAS NPDWR. Monitored under UCMR5. No EWG health guideline established due to limited toxicological data.

Where does adona come from?

Industrial use as a polymerisation aid in fluoropolymer manufacturing, developed as a PFOA replacement. Detected in water near manufacturing facilities. Included in UCMR5 due to concern about PFOA replacement chemicals entering drinking water supplies.

How do I remove adona from tap water?

The most effective methods for removing adona are: Reverse osmosis (RO), NSF 58 certified RO system, Activated carbon block filter. Look for NSF-certified systems—independent certification confirms removal claims have been verified.

Is adona in your water?

Enter your ZIP code to see the measured level in your specific utility.